Plant defence reaction is associated with activation of primary metabolic pathways. Glucose-6-phosphate dehydrogenase (G6PDH), the key enzyme of the oxidative pentose phosphate (OPP), pathway is involved in plant responses to abiotic stresses and pathogenesis. Hu et al. assess the role of G6PDH in regulating plant defence response during plant-nematode interaction.
Root-knot nematode infection caused a rapid increase in G6PDH activity and protein abundance. Arabidopsis double mutant g6pd5/6 showed enhanced susceptibility, reduced ROS production, and partly suppressing the basal defence gene expression. Hu et al. propose a new aspect of G6PDH-mediated OPP pathway in plant basal defence against root-knot nematodes.
See also: 东北地理所在植物代谢途径响应根结线虫侵染的研究中取得重要进展
Hu, Y., You, J., Li, J., & Wang, C. (2018). Loss of cytosolic glucose-6-phosphate dehydrogenase increases the susceptibility of Arabidopsis thaliana to root-knot nematode infection. Annals of Botany, 123(1), 37–46. https://doi.org/10.1093/aob/mcy124