To establish infections, plant viruses effect profound alterations to host physiology that disturb endogenous processes and contribute to the development of disease symptoms. Conti et al. summarise recently described effects of Tobacco Mosaic Virus on host plant physiology.
This review focuses upon the non-canonical roles of viral proteins that bring about the modulation of host defence, through hormone imbalances, modulation of innate immunity and antiviral RNA silencing. The authors propose that a dynamic temporal and spatial scenario governs the Tobamovirus-host interaction with individual viral proteins acting in a concerted manner.