The RAM/MOR signalling network is a conserved regulatory module involved in co-ordination of stem cell maintenance, cell differentiation and polarity establishment in animals, fungi and yeast. To date, no such signalling network has been identified in plants. Zermiani et al. identify the RAM/MOR core components and transcriptional network in Arabidopsis thaliana by in silico analysis and visualize tissue-specific expression of some of its genes by in situ hybridization. The results suggest that the arabidopsis RAM/MOR pathway may be involved in stem cell maintenance and in cell differentiation in the shoot apical and inflorescence meristems and in pollen tube polarization.
This study provides the first evidence for the RAM/MOR signalling network involved in stem cell maintenance and cell differentiation in Arabidopsis thaliana